Module Handbook

  • Dynamischer Default-Fachbereich geändert auf BIO

Notes on the module handbook of the department Bio­logy

The below displayed informations on the courses of study, modules and courses of the department of Biology are still under construction. Till this process will be finished please use our module handbooks on

https://www.bio.uni-kl.de/studium-lehre/studiengaenge/

Module BIO-TM1-4_2-M-5

Theoretical Module 1-4: Lecture and Reading Course - Mass Spectrometry and Deep Sequencing based Strategies in Systems Biology (M, 3.0 LP)

Module Identification

Module Number Module Name CP (Effort)
BIO-TM1-4_2-M-5 Theoretical Module 1-4: Lecture and Reading Course - Mass Spectrometry and Deep Sequencing based Strategies in Systems Biology 3.0 CP (90 h)

Basedata

CP, Effort 3.0 CP = 90 h
Position of the semester 1 Sem. in WiSe
Level [5] Master (Entry Level)
Language [EN] English
Module Manager
Lecturers
Area of study [BIO-BTE] Molecular Biotechnology and Systems Biology
Reference course of study [BIO-88.Z10-SG] M.Sc. Biology
Livecycle-State [NORM] Active

Courses

Type/SWS Course Number Title Choice in
Module-Part
Presence-Time /
Self-Study
SL SL is
required for exa.
PL CP Sem.
S BIO-BTE-01-K-5
Lecture and Reading Course - Mass Spectrometry and Deep Sequencing based Strategies in Systems Biology
P 24 h 66 h
TEILN
- PL1 3.0 WiSe
  • About [BIO-BTE-01-K-5]: Title: "Lecture and Reading Course - Mass Spectrometry and Deep Sequencing based Strategies in Systems Biology"; Presence-Time: 24 h; Self-Study: 66 h
  • About [BIO-BTE-01-K-5]: The study achievement [TEILN] continuous and active participation in the courses must be obtained.

Examination achievement PL1

  • Form of examination: written exam (Klausur) (60-90 Min.)
  • Examination Frequency: each winter semester

Evaluation of grades

The grade of the module examination is also the module grade.


Contents

The students will hear introductory lectures, read research and review papers, and discuss together and with the teacher the following topics:

− Hardware and device

− Deep sequencing techniques

− Quantitative proteomics strategies

− Experimental design using deep sequencing technology and quantitative proteomics

Competencies / intended learning achievements

Professional competence:

− Understanding the molecular basis of current next generation sequencing (NGS) methods.

− Knowledge on how mass analyzers work and how they are implemented in modern mass spectrometers

− Understanding how peptide sequences can be identified from fragment spectra and how protein abundance can be estimated from mass spectra

− Gaining fundamental knowlege of the different approaches and experimental basics to use deep sequencing and MS-based methods

Methodological competence: ---

Social competence:

− Learning to discuss scientific issues with other students and the teacher and explaining complex concepts

− Learning to simplify complicated topics and ideas and to identify their key aspects

Self-competence:

− Acquirement of scientific knowledge by self-responsible reading of English research literature and identification of aspects that require further explanation

− Critical evaluation of current research data

Intended Learning Outcomes:

On successfully completing the module students will be able to…

− understand the molecular and technological basis of NGS and MS-based methods.

− read and understand English literature on Systems Biology approaches.

− read and discuss research papers orally.

Literature

Bioanalytik, F. Lottspeich, J.W. Engels 2012, Springer Spektrum;

original/review articles will be provided at or prior to the beginning of the course

Materials

PDFs of lecture and literature for seminar will be provided on the homepage of the department Molecular Biotechnology & Systems Biology

Requirements for attendance (informal)

Bachelor-grade knowledge in Molecular Biotechnology, Genetics, Biochemistry, and Cell Biology

Requirements for attendance (formal)

References to Module / Module Number [BIO-TM1-4_2-M-5]

Course of Study Section Choice/Obligation
[BIO-88.Z10-SG] M.Sc. Biology Theoretical Modules 1-4: Lectures and Reading Courses [P/WP] Compulsory or compulsory elective (depending on the chosen specialization / study profile)