Module Handbook

  • Dynamischer Default-Fachbereich geändert auf MV

Notes on the module handbook of the department Mechanical and Process Engineering

Die hier dargestellten veröffentlichten Studiengang-, Modul- und Kursdaten des Fachbereichs Maschinenbau und Verfahrenstechnik ersetzen die Modulbeschreibungen im KIS und wuden mit Ausnahme folgender Studiengänge am 28.10.2020 verabschiedet.


Course MV-BioVT-86433-K-7

Downstream Processing in Biotechnology II (1V+1U, 3.0 LP)

Course Type

SWS Type Course Form CP (Effort) Presence-Time / Self-Study
- K Lecture with exercise classes (V/U) 3.0 CP 62 h
1 V Lecture 14 h
1 U Lecture hall exercise class 14 h
(1V+1U) 3.0 CP 28 h 62 h


CP, Effort 3.0 CP = 90 h
Position of the semester 1 Sem. in WiSe
Level [7] Master (Advanced)
Language [DE/EN] German or English as required
Area of study [MV-BioVT] Bioprocess Engineering
Additional informations
Livecycle-State [NORM] Active


  • Repeated introduction to the topic of downstream processing of bioprocesses (cell harvesting, digestion, coarse and fine purification of products)
  • Affinity processes in the purification (e.g. membrane adsorbers, TAGs)
  • Magnetic separation processes
  • Electrical separation processes (e.g. electrophoresis, electrodialysis)
  • Solvent extraction in bioprocess technology
  • Isolation of cells (e.g. cytometry, isolation of stem cells)

The procedures are explained using practical examples. The focus is on microbial processes as well as the processing of fermentations of animal and plant cells.

Competencies / intended learning achievements

The students are able to
  • to reproduce advanced chromatography
  • to explain affinity processes (e.g. membrane adsorbers) and electrical separation processes (e.g. electrophoresis, electrodialysis)
  • to calculate magnetic separation processes
  • to explain drying and crystallization processes
  • to independently develop and dimension a purification process for a given bioprocess


Current literature will be made available in the lecture.


Lecture notes, print and digital media. For further information and course materials please consider the corresponding OLAT-course.

Requirements for attendance (informal)

Recommended requirements:

In-depth knowledge of bioprocessing technology (e.g. through appropriate BSc. degree) and knowledge of basic operations in downstream processing (cell harvesting, filtration, chromatography, product purification).

Requirements for attendance (formal)


References to Course [MV-BioVT-86433-K-7]

Module Name Context
[MV-BioVT-122-M-7] Downstream Processing in Biotechnology II P: Obligatory 1V+1U, 3.0 LP
[MV-BioVT-M103-M-7] Bioprocess Engineering II P: Obligatory 1V+1U, 3.0 LP