Module Handbook

  • Dynamischer Default-Fachbereich geändert auf MV

Notes on the module handbook of the department Mechanical and Process Engineering

Die hier dargestellten veröffentlichten Studiengang-, Modul- und Kursdaten des Fachbereichs Maschinenbau und Verfahrenstechnik ersetzen die Modulbeschreibungen im KIS und wuden mit Ausnahme folgender Studiengänge am 28.10.2020 verabschiedet.


Course MV-BioVT-86432-K-7

Bioprocess Engineering II (2V+1U, 6.0 LP)

Course Type

SWS Type Course Form CP (Effort) Presence-Time / Self-Study
- K Lecture with exercise classes (V/U) 6.0 CP 138 h
2 V Lecture 28 h
1 U Lecture hall exercise class 14 h
(2V+1U) 6.0 CP 42 h 138 h


CP, Effort 6.0 CP = 180 h
Position of the semester 1 Sem. in SuSe
Level [7] Master (Advanced)
Language [DE/EN] German or English as required
Area of study [MV-BioVT] Bioprocess Engineering
Additional informations
Livecycle-State [NORM] Active


The module is divided into two equally weighted blocks. In the first block special procedures of bioprocess technology are discussed:
  • Cultivation of plant cells (auxotrophic and phototrophic)
  • Animal cell cultures
  • Insect cells
  • Marine Biotechnology
  • Single-Use Systems
  • Industrial Biocatalysis

In the second block, the following topics are covered:

  • Principles of bioprocess modelling
  • Introduction to Berkeley Madonna
  • Examples of dynamic bioprocess simulation
  • Evaluation of bioprocesses under the aspect of sustainability
  • Introduction to SuperProDesigner
  • Case studies

Competencies / intended learning achievements

1. Lecture

The students are able

  • to realize technical bioprocesses with different cell systems
  • to evaluate the use of animal cell cultures in human protein production
  • to explain differences between prokaryotic and eukaryotic production systems
  • to combine biological system parameters with process engineering parameters and to calculate processes independently
  • to name process strategies using phototrophic organisms.
  • to explain and analyze complex biotechnological processes

2. Exercise

The students are able

  • to model and simulate bioprocesses with appropriate software tools
  • to analyze and independently set up complex modeling and simulation of bioprocesses
  • to present and discuss their results in the exercise group
  • to assign kinetic parameters to different bioprocesses


  • I.J. Dunn, E. Heinzle, J. Ingham, J.E. Prenosil; Biological Reaction Engineering; Wiley-VCH ISBN 3-527-29776-6
  • E. Heinzle, A. Biwer, C. Cooney; Development of Sustainable Bioprocesses; Wiley ISBN-10 0-470-01559-4


Print and digital media. For further information and course materials please consider the corresponding OLAT-course.

Requirements for attendance (informal)

Recommended requirements:

In-depth knowledge of bioprocess engineering and knowledge of general process engineering and higher mathematics (e.g. by appropriate BSc. degree).

Requirements for attendance (formal)


References to Course [MV-BioVT-86432-K-7]

Module Name Context
[MV-BioVT-120-M-7] Bioprocess Engineering II P: Obligatory 2V+1U, 6.0 LP
[MV-BioVT-M102-M-4] Bioprocess Engineering I P: Obligatory 2V+1U, 5.0 LP