This course aims at introducing students to modern methods of cell and neurobiology with a focus on vesicular membrane protein transport, a process which is equally crucial for neurotransmitter release and synaptic plasticity. To familiarize students with literature research and experimental design, we will start by handing out research questions which we want to address in the course. Students are then asked to find an experimental strategy and protocol to address the given question and to present their results in our introductory seminar. The practical course work will be performed in small teams of 2(-3) students under the supervision of a Ph.D. student. Methodologically, we will employ for example different assays to analyze endocytic events and their consequences including multi-colour live cell microscopy. Following up on their experimental work, students will present their results as a powerpoint presentation in front of the group and prepare a protocol.