Module Handbook

  • Dynamischer Default-Fachbereich geändert auf BIO

Course BIO-MGE-01-K-5

Genetics, Genomics and Epigenetics (S, 3.0 LP)

Course Type

SWS Type Course Form CP (Effort) Presence-Time / Self-Study
- S Reading course 3.0 CP 20 h 70 h
(S) 3.0 CP 20 h 70 h

Basedata

SWS S
CP, Effort 3.0 CP = 90 h
Position of the semester 1 Sem. in WiSe
Level [5] Master (Entry Level)
Language [EN] English
Lecturers
Area of study [BIO-MGE] Molecular Genetics
Livecycle-State [NORM] Active

Possible Study achievement

  • Verification of study performance: continuous and active participation in the courses
  • Details of the examination (type, duration, criteria) will be announced at the beginning of the course.

Contents

− The students will hear introductory lectures on Genetics, Genomics&Epigenetics read selected chapters of the books “21st Century Genetics” and “Epigenetics” and engage in daily summary lectures with extensive discussions on the selected topics with peers and the teacher.

− Following topics will be included: Chemical and physical basis of molecular genetics; Nucleic acid structure and function and its modifications by genetic engineering; Gene expression and its regulation; Epigenetics; Cell cycle and maintenance of genome integrity; Genomics; Human genetics and genomics; Cancer as a genome disease.

Competencies / intended learning achievements

Professional competence:

− Understanding the molecular basis of the genetic and epigenetic determinants of cellular functions.

− Understanding, interpreting and presenting complex concepts of inheritance and the interplay between genetics and environment.

− Acquiring a general knowledge of the fast moving field of molecular genetics and genomics.

− Reading a comprehensive textbook, summarizing the central ideas and discussing these with other students.

Methodological competence:

− Understanding classical key experiments and the basis of their design and how their results contributed in our knowledge of molecular genetics; novel concepts of genomics and epigenetics.

− Ability to explain the key experiments and conceptes to others.

Social competence:

− Learning to discuss scientific issues with other students and the teacher and explaining complex concepts.

− Learning to simplify complicated topics and ideas and to identify their key aspects.

Self-competence:

− Acquiring scientific knowledge through first supervised and subsequently self-directed reading of English research literature and identifying points that require further explanation. Discussing with peers and the teacher.

− Independent critical evaluation of current research data, identification of experimental strength and weaknesses.

Intended Learning Outcomes:

On successfully completing the module students will be able to…

− acquire a broad overview about the field of current molecular genetics and genomics.

− read and understand an advanced English textbook.

− summarize and discuss the complex concepts of molecular genetics.

Literature

Grodzicker, Stewart, Stillman: 21st Century Genetics Allis, Caparros, Jenuwein, Reinberg: Epigenetics

Materials

Will be provided at or prior to the beginning of the course

Requirements for attendance (informal)

Bachelor-grade knowledge in molecular biology and genetics, organic chemistry and biochemistry, cell biolog

Requirements for attendance (formal)

Admission to the Master Program ‘Biology’

References to Course [BIO-MGE-01-K-5]

Course-Pool Name
[BIO-LR_all-KPOOL-5] Lecture & Reading Course - all
[BIO-LR_MCB-KPOOL-5] Lecture & Reading Course: MCB
[BIO-LR_MPBiotech-KPOOL-5] Lecture & Reading Course: MPBiotech