Mass Spectrometry and Deep sequencing Based Strategies in Systems Biology (S, 3.0 LP)
|SWS||Type||Course Form||CP (Effort)||Presence-Time / Self-Study|
|-||S||Reading course||3.0 CP||24 h||66 h|
|(S)||3.0 CP||24 h||66 h|
|CP, Effort||3.0 CP = 90 h|
|Position of the semester||1 Sem. in WiSe|
|Level|| Master (Entry Level)|
|Area of study||[BIO-BTE] Molecular Biotechnology and Systems Biology|
Possible Study achievement
- Verification of study performance: continuous and active participation in the courses
- Details of the examination (type, duration, criteria) will be announced at the beginning of the course.
− Hardware and device
− Deep sequencing techniques
− Quantitative proteomics strategies
− Experimental design using deep sequencing technology and quantitative proteomics
Competencies / intended learning achievements
− Understanding the molecular basis of current next generation sequencing (NGS) methods.
− Knowledge on how mass analyzers work and how they are implemented in modern mass spectrometers
− Understanding how peptide sequences can be identified from fragment spectra and how protein abundance can be estimated from mass spectra
− Gaining fundamental knowlege of the different approaches and experimental basics to use deep sequencing and MS-based methods
− Learning to discuss scientific issues with other students and the teacher and explaining complex concepts
− Learning to simplify complicated topics and ideas and to identify their key aspects
− Acquirement of scientific knowledge by self-responsible reading of English research literature and identification of aspects that require further expllanation
− Critical evaluation of current research data
Intended Learning Outcomes:
On successfully completing the module students will be able to…
− understand the molecular and technological basis of NGS and MS-based methods.
− read and understand English literature on Systems Biology approaches.
− read and discuss research papers orally